Advitech

Background
For centuries, milk and milk-derived products have been an essential part of our daily diet. Milk not only provides nutrition to newborn babies, but also a wide variety of active ingredients that protect against microbial pathogens and promote the development of the immune system. These active ingredients include growth factors such as TGF-β (1 and 2) and IGF (1 and 2).

Product
Through its extensive research program, Advitech can now use the health-benefiting properties of milk-derived growth factors to develop products with specific and proven applications for targeted health disorders.

XP-828L is a patent-pending composition of growth factors, comprised mainly of TGF-β and IGF, obtained from whey using a combination of physical and chemical processes.

TGF-β is a multi-functional regulator of cell functions and a powerful modulator of the immune system making TGF-β useful in treating impaired wound healing, mucositis, and autoimmune diseases¹.

IGF has insulin-like effects in adipose tissue and skeletal muscles and may therefore be useful in the treatment of insulin resistance, metabolic syndrome with or without diabetes, and growth-related health disorders². Also, IGF has been known to play an important role in multiple sclerosis³ and degenerative diseases⁴.

¹Gorelik L and Flavell R.A. Nat Rev Immunol. 2002 2(1):46-53.
²LeRoith D and Yakar S. Nat Clin Pract Endocrinol Metab. 2007 3(3):302-10.
³Chesik D et al. Int Rev Neurobiol 2007 79:203-26.
⁴Trejo JL et al. J Mol Med 2004 82(3) :156-62.